Effect of Body Mass Index on Intracytoplasmic 81 Sperm Injection Outcomes


  • Mahwish Mengal, Shazia Ali, Nasim Ashraf, Anjum Siddiqui, Arif Siddiqui


Obesity, Oocyte Quality, Embryo Quality, ICSI Outcomes, Infertility.


Objective: To determine the effects of increased BMI on ICSI outcomes.
Study Design: It was an analytical cross sectional study.
Place and Duration of Study: Islamabad Clinic Serving Infertile Couples, Islamabad, Pakistan. Duration of the study was one year, from January 2013 to December 2013.
Materials and Methods: Total of 150 females were classified into three groups on the basis of BMI. Those with BMI ranging
from 18.5 - 24.9 kg/m2 /were placed in normal group [n=50], those with BMI ranging from 25 - 29.9 kg/m2/were placed in overweight group [n=50] and those with BMI ranging more than 30kg/ m2 were placed in obese group [n=50]. Serum levels of FSH, LH, Te, TSH, T3 and T4 were done in all three groups and their effects on oocyte and embryo quality were observed during controlled ovarian stimulation and after ICSI procedure.
Results: Obese group had significantly decreased ICSI outcomes due to increased levels of testosterone (p value< 0.05).
Conclusion: Increased BMI leads to decreased ICSI outcomes