Identification Of Bacterial Isolates and Antimicrobial Susceptibility Pattern Among Patients Diagnosed with Surgical Site Infections
Bacterial Isolates and Antimicrobial Susceptibility Pattern
Keywords:
Surgical site infections, surgical wounds, bacterial isolates, antimicrobial susceptibilityAbstract
Background: Despite the use of prophylactic antibiotics and preventive measures, surgical site infections (SSIs) continue to be a common postoperative complication, attributed mostly to increasing antimicrobial resistance.
Objective: To investigate the bacterial profile and antimicrobial susceptibility patterns of isolates from patients diagnosed with SSIs at Jinnah Hospital, Lahore, Pakistan.
Methodology: A cross-sectional study design was used for sampling, and 65 surgical wound samples were collected from admitted patients. All specimens (Pus and wound swabs) were collected for bacterial isolation, identification, and antimicrobial testing using standard microbiological techniques. SPSS software was used for statistical analysis, and a P value (<0.05) was considered statistically significant.
Results: This research found that SSIs were found in 24 (37%) of patients who belonged to the 16-30 years of age group. More males, 41(63%), were affected as compared to females. SSIs were more common in the lower extremities 43 (66%). The majority of patients, 30(46%) were diagnosed with double microbial infections at SSIs. More males, 14 (22%) developed SSIs due to E. coli (P<0.05), and double microbial infection was also common in males (P < 0.05). MRSA was found resistant to antimicrobial drugs, while S. aureus was found sensitive to antimicrobial drugs. (P value<0.05).
Conclusion: In our study, SSIs were found prevalent in the lower extremities and mostly due to double microbial infections. E. coli was found to cause SSIs in males.
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