Neurodegenerative Disorders and Antioxidants; A Review

Abstract

This study aims to review the association between nutrient metabolism and the development of degenerative diseases. Over the years, the rate of degenerative diseases has increased along with other issues. Degenerative diseases can be defined as diseases that develop when the ability of the tissues and cells to function optimally is dysfunctional or lost. The causes of degenerative diseases can be complex and multi-factorial and may include genetics, lifestyle factors, environmental factors, aging and chronic health conditions. The most common factors include inflammation and oxidative stress that leads to the development and growth of degenerative diseases. The high quantities of ROS in the environment have prompted the evolution of several protective systems in animals. Dietary recommendations need to be strictly considered to increase the antioxidants in the diet. These antioxidants will work as a preventive measure against degenerative diseases. Reactive Oxygen Species are mostly neutralized by Vitamin C which is acting as a reducing agent. Conclusively, the progression of degenerative disorders affects nutrient metabolism and likewise, intake of healthy nutrients prevents the development of degenerative ailments.