Prevalence and Antimicrobial Sensitivity Pattern of Staphylococcus saprophyticus isolated from Urinary Tract Infection in Women

Abstract

Background: Staphylococci saprophyticus are Gram-positive, coagulase-negative, non hemolytic cocci which cause urinary tract infections in young adult women.
Objective: The present study aimed to investigate the prevalence and antimicrobial sensitivity pattern of S. saprophyticus isolated from young women with urinary tract infection.
Methodology: A total of 100 urine samples were collected from urinary tract infected women at Government General Hospital, Faisalabad. Samples were transported and proceeded in Microbiology laboratory of Riphah international university, Faisalabad. The isolated S. saprophyticus were identified by Gram staining, culture characteristics, biochemical tests and by antimicrobial (Novobiocin) sensitivity test by Modified Kirby Bauer disc diffusion method.
Results: Ninety-four (94) out of 100 urine samples revealed growth of gram positive bacteria, gram negative bacteria and fungi on different culture media. S. saprophyticus was recovered from 3 urine samples. All strains of S. saprophyticus (100%) were found sensitive to imipenem and amikacin. Out of 3, two isolates (66.6%) showed sensitivity against gentamicin and ciprofloxacin. However, all isolated S. saprophyticus were found resistant to pipemidic acid and nitrofurantoin.

Conclusion: These findings contribute to the understanding of infections caused by S. saprophyticus and may aid in the selection of appropriate antibiotics for the treatment of urinary tract infections