Prevalence of ABH Secretor and non-secretor Among Population of Lahore

Abstract

Background: ABO blood groups and secretor status of person are genetically inherited and have imperative role in forensic and clinical medicine. Although the distribution of secretor’s status and non-secretor status diverges widely in relation to ABO groups in populations across the world due to racial and geographical differences. In Pakistan, there is no specific work done on ratio of secretor and non-secretor particularly in the population of Lahore.

Objective: The main objective of the study was to assess the ABO grouping and secretor status of different ABO groups among the general population of Lahore (Pakistan).

Methodology: Samples of saliva and blood were collected from 101 study participants (26 girls and 75 boys) of Lahore who participated in this study. Conventional tile and tube methods were performed to find out the blood group and the presence of secretor and non-secretor status by using hemagglutination Inhibition technique. Results: It was found that 56.4% of individuals were secretors and 43.6% were non-secretors. In 101 individuals, the percentage of A, B, AB and O group was 23.8%, 39.6%, 7.9% and 28.7% respectively. Among A, B, AB and O groups observed frequency of secretors was 58.3%, 60%, 75% and 44.8% respectively. The prevalence of Rh +ve and Rh –ve in given individuals were 84.2% and 15.8% respectively.

Conclusion: Current study concluded that the order of ABO grouping is B>O>A>AB and the rate of secretor status is much higher than non-secretor status. The ABH non-secretors have a high acceptance rate of getting auto-immune disorders like multiple sclerosis and reactive arthritis etc.