LETTER TO THE EDITOR: Food-added Monosodium Glutamate does not induce Changes in the Ovaries

Abstract

Ajinomoto Group is one of the leading global producers of the flavor enhancer monosodium glutamate (MSG). Since early 20th century,Ajinomoto has gathered a substantial amount of data related to MSG safety and use. Based on that database, we are commenting here-below on the recent article by Abbasi et al., entitled “Effect of Vitamin C on monosodium glutamate (Ajinomoto)
induced changes in the ovary of rats” (JIIMC 11(2), 2016, 66-70).
The article described a rat study with MSG and vitamin C. The authors extensively speculated that MSG ingestion may cause harmful effects on human female fertility and ovarian functions. We argue that the study by Abbasi et al. was burdened by
methodological problems and a lack of reproducibility. In addition, we conclude that the authors neglected glutamate metabolism in mammalian bodies in interpreting the results.........................