Diabetic Nephropathy: Duration and Glycemic Control Affect the Outcome

Abstract

Objective: The aim was to find out frequency of Nephropathy in subjects having type 2 Diabetes Mellitus; and to determine the effect of disease duration and blood glucose levels on the development of Diabetic nephropathy.
Study Design: Cross-sectional.
Place and Duration of Study: POF Hospital Wah Cantt, 1st January to 30th June 2018.
Materials and Methods: Two hundred and ten subjects were enrolled having Type-2 Diabetes for more than 5 years. A closed ended questionnaire was used to record information on disease duration, glycosylated hemoglobin level, blood pressure and albuminuria. The data was analyzed by SPSS v-19 and significance of results was studied by Chi-square test.
Results: Among 210 patients 126 were male and 84 were female. Out of 210 people under study 54.76% had Diabetic Nephropathy. Significantly a greater number of Diabetic Nephropathy was recorded among subjects having Diabetes for more than 10 years (p-values 0.03), and whose blood sugar levels were never controlled (pvalues 0.000).
Conclusion: The frequency of Diabetic Nephropathy was found to be quite high. It was significantly higher among subjects having diabetes for longer duration and uncontrolled blood sugar levels. Therefore, it is essential to monitor these patients regularly to prevent complications and improve their health.